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王静,艾力·苏,王迪,许忆峰,刘婷婷,黄勤.新疆和田县健康体检人群甲状腺结节患病情况及危险因素分析[J].Academic Journal of Second Military Medical University ,2019,40(6):637-642
新疆和田县健康体检人群甲状腺结节患病情况及危险因素分析    点此下载全文 Fulltext
王静1  艾力·苏2  王迪3  许忆峰1  刘婷婷1  黄勤1*
1. 海军军医大学(第二军医大学)
长海医院内分泌科, 上海 200433;
2. 和田地区人民医院呼吸科, 和田 848000;
3. 乌鲁木齐市中医医院内分泌科, 乌鲁木齐 830000
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      目的 分析新疆和田县人民医院健康体检人群中甲状腺结节患病情况和相关危险因素,为甲状腺疾病的防治提供依据。方法 回顾性分析2016年5月至2018年1月在和田县人民医院健康体检中心进行健康体检的18岁以上人群的检查资料,选择应用彩色多普勒超声诊断仪进行甲状腺超声检查并有完整资料的健康体检者作为研究对象。根据超声检查结果,将符合纳入标准的健康体检者分为甲状腺结节组和非甲状腺结节组,对提取的数据进行单因素分析和多因素logistic回归分析。结果 纳入研究的健康体检者共2 752名,男1 631名、女1 121名,平均年龄为(45.29±13.13)岁。甲状腺结节总患病率为35.6%(980/2 752),甲状腺结节患病率随年龄增长呈递增趋势(P<0.01),男性患病率(32.5%,530/1 631)低于女性(40.1%,450/1 121),差异有统计学意义(P<0.01)。多因素logistic回归分析显示年龄、肥胖、空腹血糖和三酰甘油是甲状腺结节发生的独立危险因素(P均<0.05)。结论 和田县人民医院健康体检人群中甲状腺结节的患病率维持在一个较高的水平,随年龄增长患病率逐渐升高,且女性患病率高于男性。年龄、肥胖、空腹血糖、三酰甘油是甲状腺结节发生的独立危险因素,对早期发现甲状腺结节有提示作用。
关键词:甲状腺结节  体格检查  患病率  危险因素
Prevalence and risk factors of thyroid nodules in physical examination population in Hotan county, Xinjiang    Fulltext
WANG Jing1  Aili Su2  WANG Di3  XU Yi-feng1  LIU Ting-ting1  HUANG Qin1*
1. Department of Endocrinology, Changhai Hospital, Naval Medical University(Second Military Medical University)
, Shanghai 200433, China;
2. Department of Respiration, People's Hospital of Hotan District, Hotan 848000, Xinjiang Uygur Autonomous Region, China;
3. Department of Endocrinology, Urumqi Municipality Chinese Medicine Hospital, Urumqi 830000, Xinjiang Uygur Autonomous Region, China
*Corresponding author
Fund Project:Supported by General Program of National Natural Science Foundation of China (81471038, 81272665) and Science Research Fund for Public Welfare Industries of National Health and Family Planning Commission (201502011).
      Objective To investigate the prevalence and risk factors of thyroid nodules in physical examination population of Hotan County People's Hospital, so as to provide a basis for the prevention and treatment of thyroid diseases. Methods A retrospective analysis was conducted on the data of population over 18 years old who underwent physical examination in the Health Examination Center of Hotan County People's Hospital from May 2016 to Jan. 2018. All enrolled subjects underwent thyroid ultrasonography and had complete ultrasonographic information. The subjects were divided into thyroid nodule group and non-thyroid nodule group. Univariate analysis and multivariate logistic regression analysis were performed to analyze the risk factors of thyroid nodules. Results A total of 2 752 subjects were enrolled in this study, including 1 631 males and 1 121 females. The total prevalence rate of thyroid nodules was 35.6% (980/2 752), and the prevalence rate of thyroid nodules in males was significantly lower than that in females (32.5%[530/1 631] vs 40.1%[450/1 121], P<0.01). The prevalence rate of thyroid nodules increased gradually with age (P<0.01). Multivariate logistic regression analysis showed that age, obesity, fasting plasma glucose and triglyceride were independent risk factors of thyroid nodules (all P<0.05). Conclusion The prevalence of thyroid nodules maintains at a higher level in the physical examination population of Hetian County People's Hospital, and gradually increases with age. The prevalence rate in females is higher than that in males. Age, obesity, fasting plasma glucose and triglyceride are independent risk factors of thyroid nodules, and may help the early detection of thyroid nodules.
Keywords:thyroid nodule  physical examination  prevalence rate  risk factors
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