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  • 周国武△,胡佳△,高峻*.内镜下逆行胰胆管造影术后胰腺炎的非药物预防研究进展[J].第二军医大学学报,2010,31(2):200-203    [点击复制]
  • ZHOU Guo-wu△, HU Jia△, GAO Jun*.Department of Endocrinology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China[J].Acad J Sec Mil Med Univ,2010,31(2):200-203   [点击复制]
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内镜下逆行胰胆管造影术后胰腺炎的非药物预防研究进展
周国武△,胡佳△,高峻*
0
(第二军医大学长海医院消化内科,上海 200433)
摘要:
内镜下逆行胰胆管造影术(ERCP)已成为目前消化系统疾病的重要临床诊断及治疗手段,但其术后胰腺炎(post-ERCP pancreatitis,PEP)等并发症的高发病率大大限制了临床应用,亦给患者生命带来了严重威胁。预防PEP成为ERCP相关研究的热点。药物预防PEP的现状不容乐观,目前尚无一种药物可有效预防PEP;然而,非药物措施,如胰管支架植入术、导丝引导插管等在PEP的预防中显示出良好的效果,为 PEP的有效预防带来了新希望。本文就非药物预防措施预防PEP的研究现状作一综述。
关键词:  内镜逆行胰胆管造影术  胰腺炎  胰管支架  导丝引导插管
DOI:10.3724/SP.J.1008.2010.0200
投稿时间:2009-10-15修订日期:2009-12-25
基金项目:
Department of Endocrinology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
ZHOU Guo-wu△, HU Jia△, GAO Jun*
(Department of Endocrinology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China)
Abstract:
ERCP has become an important method for diagnosis and treatment of digestive diseases, but the high incidences of post-ERCP complications (PEP), especially for post-ERCP pancreatitis, have limited its application. Prevention of PEP has become a focus of ERCP-related studies.Current drug prevention of PEP is not satisfactory, and there has not been a single drug which can effectively prevent PEP. In contrast, non-pharmacologic preventive techniques such as pancreatic stent placing and guide wire cannulation have been proven to have prominent effects in preventing PEP, which brings new hopes for PEP prevention. This paper reviews the studies on non-pharmacologic prevention of PEP.
Key words:  endoscopic retrograde cholangiopancreatography  pancreatitis  pancreatic stent  guide wire cannulation